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In nine patients, one with bilateral findings, impending gangrene of the hand due
to thrombosis of the palmar arch or digital arteries did not respond to current surgical
methods or to common nonsurgical measures and was treated by intra-arterial Thrombolysin.
The authors recommended diagnostic arteriography, direct surgical treatment, if indicated,
and specific coagulation studies. Thrombolysin was given by perfusion at a rate of
100,000 U. per hour. Careful monitoring of the clotting process prevented any significant
bleeding and excellent recovery occurred in eight hands and there was a good result
in two.
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Article info
Publication history
Received:
February 9,
1976
Identification
Copyright
© 1976 American Society for Surgery of the Hand. Published by Elsevier Inc. All rights reserved.
