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Hand Allodynia, Lack of Finger Flexion, and the Need for Carpal Tunnel Release

Published:March 02, 2023DOI:https://doi.org/10.1016/j.jhsa.2023.01.001

      Purpose

      The clinical features of classic carpal tunnel syndrome are well known. However, some patients who may respond equally well to carpal tunnel release (CTR) display atypical signs and symptoms. The chief differential features are allodynia (painful dysesthesias), lack of finger flexion, and, on examination, pain on passive finger flexion. The goal of the study was to present the clinical features, increase awareness, facilitate accurate diagnosis, and report the outcomes after surgery.

      Methods

      Thirty-five hands, from 22 patients with the main features of allodynia and lack of full finger flexion, were gathered in the period 2014–2021. The other common complaints included sleeping disturbances (20 patients), hand swelling (31 hands), and shoulder pain on the same side as the hand problem with limited range of motion (30 sides). The Tinel or Phalen signs were obscured by the pain. However, pain with passive flexion of the fingers was universally present. All the patients were treated with carpal tunnel release through a mini-incision approach: four patients had a trigger finger, which was treated concomitantly in six hands, and one patient underwent contralateral CTR for carpal tunnel syndrome with a more standard presentation.

      Results

      At a minimum of 6 months of follow-up (mean, 22 months; range, 6–60 months), the pain decreased by 7.5 ± 1.9 points on the Numerical Rating Scale, which ranges from 0 to 10. The pulp-to-palm distance improved from 3.7 to 0.3 cm. The mean Disabilities of the Arm, Shoulder, and Hand score decreased from 67 to 20. The mean Single-Assessment Numeric Evaluation score for the whole group was 9.7 ± 0.6.

      Conclusions

      Hand allodynia and lack of finger flexion may be indications of median neuropathy in the carpal canal, which responds to CTR. Awareness of this condition is important because the uncharacteristic clinical presentation may not be considered an indication for surgery that can be beneficial.

      Type of study/level of evidence

      Therapeutic IV.

      Key words

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      References

        • McCabe S.J.
        Diagnosis of carpal tunnel syndrome.
        J Hand Surg Am. 2010; 35: 646-648
        • Graham B.
        • Regehr G.
        • Naglie G.
        • Wright J.G.
        Development and validation of diagnostic criteria for carpal tunnel syndrome.
        J Hand Surg Am. 2006; 31: 919-924
        • Graham B.
        The value added by electrodiagnostic testing in the diagnosis of carpal tunnel syndrome.
        J Bone Joint Surg Am. 2008; 90: 2587-2593
        • American Academy of Orthopaedic Surgeons
        Management of Carpal Tunnel Syndrome Evidence-Based Clinical Practice Guideline.
        • Billig J.I.
        • Sears E.D.
        Utilization of diagnostic testing for carpal tunnel syndrome: a survey of the American Society for Surgery of the Hand.
        J Hand Surg Am. 2022; 47: 11-18
        • Del Piñal F.
        Reflex sympathetic dystrophy (RSD)/CRPS/Sudeck does not exist.
        Ezine (IFSSH). 2019; 9: 22-31
        • Del Piñal F.
        Outcomes of carpal tunnel release in complex regional pain syndrome/reflex sympathetic dystrophy/Sudeck disease patients.
        Plast Reconstr Surg. 2022; 150: 93-101
      1. Del Piñal F. Diagnosis and outcomes of 225 consecutive cases of CRPS of the hand. Plast Reconstr Surg. In press.

        • Birch R.
        The diagnosis of neuropathic pain after injury to a nerve.
        in: Birch R. Peripheral Nerve Injuries: A Clinical Guide. Springer-Verlag, 2013: 184-191
        • Koman A.L.
        • Smith B.P.
        • SmithTL
        A practical guide for complex regional pain syndrome in the acute stage and late stage.
        in: Wolfe S.W. Pederson W.C. Kozin S.H. Green’s Operative Hand Surgery. 8th ed. Churchill Livingstone, 2021: 2005-2035
        • Farrar J.T.
        • Young Jr., J.P.
        • LaMoreaux L.
        • Werth J.L.
        • Poole M.R.
        Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale.
        Pain. 2001; 94: 149-158
        • Rosales R.S.
        • Delgado E.B.
        • de la Lastra-Bosch I.D.
        Evaluation of the Spanish version of the DASH and carpal tunnel syndrome health-related quality-of-life instruments: cross-cultural adaptation process and reliability.
        J Hand Surg Am. 2002; 27: 334-343
        • Gire J.D.
        • Koltsov J.C.
        • Segovia N.A.
        • Kenney D.E.
        • Yao J.
        • Ladd A.L.
        Single Assessment Numeric Evaluation (SANE) in hand surgery: does a one-question outcome instrument compare favorably?.
        J Hand Surg Am. 2020; 45: 589-596
        • Levine D.W.
        • Simmons B.P.
        • Koris M.J.
        • et al.
        A self-administered questionnaire for the assessment of severity of symptoms and functional status in carpal tunnel syndrome.
        J Bone Joint Surg Am. 1993; 75: 1585-1592
        • Graham B.
        The Development of Diagnostic Criteria for Carpal Tunnel Syndrome.
        Dissertation. University of Toronto, 2003: 114-115
        • Crymble B.
        Brachial neuralgia and the carpal tunnel syndrome.
        Br Med J. 1968;3; : 470-471
        • Cherington M.
        Proximal pain in carpal tunnel syndrome.
        Arch Surg. 1974; 108: 69
        • Stevens J.C.
        • Smith B.E.
        • Weaver A.L.
        • Bosch E.P.
        • Deen Jr., H.G.
        • Wilkens J.A.
        Symptoms of 100 patients with electromyographically verified carpal tunnel syndrome.
        Muscle Nerve. 1999; 22: 1448-1456
        • Burke D.T.
        • Burke M.A.
        • Bell R.
        • Stewart G.W.
        • Mehdi R.S.
        • Kim H.J.
        Subjective swelling: a new sign for carpal tunnel syndrome.
        Am J Phys Med Rehabil. 1999; 78: 504-508
        • Katz J.N.
        • Stirrat C.R.
        A self-administered hand diagram for the diagnosis of carpal tunnel syndrome.
        J Hand Surg Am. 1990; 15: 360-363
        • Zyluk A.
        A new clinical severity scoring system for reflex sympathetic dystrophy of the upper limb.
        J Hand Surg Br. 2003; 28: 238-241
        • Żyluk A.
        • Mosiejczuk H.
        A comparison of the accuracy of two sets of diagnostic criteria in the early detection of complex regional pain syndrome following surgical treatment of distal radial fractures.
        J Hand Surg Eur Vol. 2013; 38: 609-615
        • Veldman P.H.
        • Reynen H.M.
        • Arntz I.E.
        • Goris R.J.
        Signs and symptoms of reflex sympathetic dystrophy: prospective study of 829 patients.
        Lancet. 1993; 342: 1012-1016
        • Schwartzman R.J.
        • Erwin K.L.
        • Alexander G.M.
        The natural history of complex regional pain syndrome.
        Clin J Pain. 2009; 25: 273-280
        • Ott S.
        • Maihöfner C.
        Signs and symptoms in 1,043 patients with complex regional pain syndrome.
        J Pain. 2018; 19: 599-611
        • Noordenbos W.
        • Wall P.D.
        Implications of the failure of nerve resection and graft to cure chronic pain produced by nerve lesions.
        J Neurol Neurosurg Psychiatry. 1981; 44: 1068-1073
        • Patterson R.W.
        • Li Z.
        • Smith B.P.
        • Smith T.L.
        • Koman L.A.
        Complex regional pain syndrome of the upper extremity.
        J Hand Surg Am. 2011; 36: 1553-1562
        • Birklein F.
        • O'Neill D.
        • Schlereth T.
        Complex regional pain syndrome: an optimistic perspective.
        Neurology. 2015; 84: 89-96
        • Bruehl S.
        Complex regional pain syndrome.
        BMJ. 2015; 351: h2730
        • Goebel A.
        • Turner-Stokes L.F.
        Complex Regional Pain Syndrome in Adults.
        in: UK Guidelines for Diagnosis, Referral and Management in Primary and Secondary Care. 2nd edition. Royal College of Physicians, London2018
        • Shim H.
        • Rose J.
        • Halle S.
        • Shekane P.
        Complex regional pain syndrome: a narrative review for the practising clinician.
        Br J Anaesth. 2019; 123: e424-e433
        • Black N.
        Why we need observational studies to evaluate the effectiveness of health care.
        BMJ. 1996; 312: 1215-1218
        • Landewé R.
        • Van Der Heijde D.
        Primer: challenges in randomized and observational studies.
        Nat Clin Pract Rheumatol. 2007; 3: 661-666
        • Dworkin R.H.
        • Turk D.C.
        • Farrar J.T.
        • et al.
        Core outcome measures for chronic pain clinical trials: IMMPACT recommendations.
        Pain. 2005; 113: 9-19
        • Wessel L.E.
        • Fufa D.T.
        • Boyer M.I.
        • Calfee R.P.
        Epidemiology of carpal tunnel syndrome in patients with single versus multiple trigger digits.
        J Hand Surg Am. 2013; 38: 49-55
        • McLellan D.L.
        Letter: longitudinal sliding of median nerve during hand movements: a contributory factor in entrapment neuropathy?.
        Lancet. 1975; 1: 633-634
        • Wilgis E.F.
        • Murphy R.
        The significance of longitudinal excursion in peripheral nerves.
        Hand Clin. 1986; 2: 761-766
        • Hunter J.M.
        Recurrent carpal tunnel syndrome, epineural fibrous fixation, and traction neuropathy.
        Hand Clin. 1991; 7: 491-504
        • Jones N.F.
        • Shaw W.W.
        • Katz R.G.
        • Angeles L.
        Circumferential wrapping of a flap around a scarred peripheral nerve for salvage of end-stage traction neuritis.
        J Hand Surg Am. 1997; 22: 527-535
        • Montgomery A.S.
        • Birch R.
        • Malone A.
        Sciatic neurostenalgia: caused by total hip arthroplasty, cured by late neurolysis.
        J Bone Joint Surg Br. 2005; 87: 410-411
        • Jones N.F.
        • Ahn H.C.
        • Eo S.
        Revision surgery for persistent and recurrent carpal tunnel syndrome and for failed carpal tunnel release.
        Plast Reconstr Surg. 2012; 129: 683-692
        • Laing T.A.
        • Sierakowski A.
        • Elliot D.
        Management of painful scar-tethered cutaneous nerves of the upper limb.
        Hand Surg Rehabil. 2017; 36: 208-214