Case repository| Volume 44, ISSUE 8, P701.e1-701.e5, August 2019

Download started.


Ewing Sarcoma in an Infant Metacarpal

Published:October 17, 2018DOI:
      We describe a case of Ewing sarcoma in the metacarpal of a 5-month-old male. After pain, erythema, and swelling of the hand failed to resolve with antibiotics, radiographs and magnetic resonance imaging raised suspicion for a neoplastic condition. Open biopsy confirmed the diagnosis of Ewing sarcoma and treatment with chemotherapy and surgical resection was initiated. Ewing sarcoma of the hand in a patient this young is an exceedingly rare diagnosis, which highlights the importance of a broad differential diagnosis when the treatments for more common conditions fail.

      Key words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Hand Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Plate A.M.
        • Steiner G.
        • Posner M.A.
        Malignant tumors of the hand and wrist.
        J Am Acad Orthop Surg. 2006; 14: 680-692
        • Durbin M.
        • Randall R.L.
        • James M.
        • Sudilovsky D.
        • Zoger S.
        Ewing's sarcoma masquerading as osteomyelitis.
        Clin Orthop Relat Res. 1998; 357: 176-185
        • Strege D.W.
        • Hanel D.P.
        • Vogler C.
        • Schajowicz F.
        Ewing sarcoma in a phalanx of an infant's finger: a case report.
        J Bone Joint Surg Am. 1989; 71: 1262-1265
        • Puhaindran M.
        • Athanasian E.
        Malignant bone and soft-tissue sarcomas of the hand.
        J Hand Surg Am. 2004; 4: 60-72
        • Euler E.
        • Wilhelm K.
        • Permanetter W.
        • Kreusser T.
        Ewing's sarcoma of the hand: localization and treatment.
        J Hand Surg Am. 1990; 15: 659-662
        • Escobedo E.M.
        • Bjorkengren A.G.
        • Moore S.G.
        Ewing’s sarcoma of the hand.
        AJR Am J Roentgenol. 1992; 159: 101-102
        • Pan H.Y.
        • Morani A.
        • Wang W.L.
        • et al.
        Prognostic factors and patterns of relapse in Ewing sarcoma patients treated with chemotherapy and R0 resection.
        Int J Radiat Oncol Biol Phys. 2015; 92: 349-357
        • Granowetter L.
        Dose-intensified compared with standard chemotherapy for nonmetastatic Ewing sarcoma family of tumors: a Children's Oncology Group study.
        J Clin Oncol. 2009; 27: 2536-2541
        • Ozaki T.
        • Hashizume H.
        • Kawai A.
        • Inoue H.
        Ewing's sarcoma of the hand: magnetic resonance images and treatment.
        J Hand Surg Am. 1995; 20: 441-444
        • Bickert B.
        • Heitmann C.
        • Germann G.
        Fibulo-scapho-lunate arthrodesis as a motion-preserving procedure after tumour resection of the distal radius.
        J Hand Surg Br. 2002; 27: 573-576
        • Harder Y.
        Primitive neuroectodermal tumor of the thumb metacarpal bone: a case report and literature review.
        J Hand Surg Am. 2003; 28: 346-352
        • Reinus W.
        • Gilula L.
        • Shiriey S.
        • Askin F.
        • Siegal G.
        Radiographic appearance of Ewing sarcoma of the hands and feet: report from the Intergroup Ewing Sarcoma Study.
        AJR Am J Roentgenol. 1985; 144: 331-336
        • Ramos-Pascua L.
        • Fernandez-Hernandez O.
        • Herraez S.
        • Sanchez J.
        • Corral T.
        Ewing sarcoma of the first metacarpal with a 9-year follow-up: case report.
        J Hand Surg Am. 2013; 38: 1575-1578
        • Dryer R.
        • Buckwalter J.
        • Flatt A.
        • Bonfiglio M.
        Ewing’s sarcoma of the hand.
        J Hand Surg Am. 1979; 4: 372-374
        • Liu Y.
        • Chen W.
        Ewing’s sarcoma of the metacarpal bone of the hand: a case report.
        J Hand Surg Am. 1998; 23: 748-752