Abstract| Volume 39, ISSUE 9, SUPPLEMENT , e3, September 2014

Effect of Delayed Finger Extension on the Efficacy and Safety of Collagenase Clostridium Histolyticum Treatment for Dupuytren Contracture

Level 2 Evidence
      Treatment of Dupuytren’s contracture with collagenase clostridium histolyticum (CCH) involves a single injection of CCH into the cord of the affected joint, followed by a finger extension procedure. The current labeling for CCH indicates that the finger extension procedure should be performed 24 hours after injection. In practice the timing of the procedure may vary since physicians may not have clinic hours on sequential days. The effect of varying time to finger extension was evaluated as part of a study of patients who received two concurrent injections of CCH to concurrently treat two affected joints of the same hand.
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