Review article| Volume 32, ISSUE 6, P893-898, July 2007

Bizarre Parosteal Osteochondromatous Proliferation and Periosteal Chondroma: A Comparative Report and Review of the Literature

      Bizarre parosteal osteochondromatous proliferation and periosteal chondroma are rare, benign, bony lesions that may present in the hand. Bizarre parosteal osteochondromatous proliferation was first reported in the literature by Nora in 1983, and periosteal chondroma was first reported by Lichtenstein in 1952. This report provides a unique side-by-side comparison of these lesions, illustrating each with a clinical vignette. This report, coupled with a thorough review of the literature, serves to demonstrate that the history and physical exam characteristics, as well as the radiographic and gross appearances, are insufficient to differentiate between the two lesions. Histopathologic examination is required to confirm the diagnosis.

      Key words

      To read this article in full you will need to make a payment

      Purchase one-time access:

      Academic & Personal: 24 hour online accessCorporate R&D Professionals: 24 hour online access
      One-time access price info
      • For academic or personal research use, select 'Academic and Personal'
      • For corporate R&D use, select 'Corporate R&D Professionals'


      Subscribe to Journal of Hand Surgery
      Already a print subscriber? Claim online access
      Already an online subscriber? Sign in
      Institutional Access: Sign in to ScienceDirect


        • Nora F.E.
        • Dahlin D.C.
        • Beabout J.W.
        Bizarre parosteal osteochondromatous proliferations of the hands and feet.
        Am J Surg Pathol. 1983; 7: 245-250
        • Michelsen H.
        • Abramovici L.
        • Steiner G.
        • Posner M.A.
        Bizarre parosteal osteochondromatous proliferation (Nora’s lesion) in the hand.
        J Hand Surg. 2004; 29A: 520-525
        • Meneses M.F.
        • Unni K.K.
        • Swee R.G.
        Bizarre parosteal osteochondromatous proliferation of bone (Nora’s lesion).
        Am J Surg Pathol. 1993; 17: 691-697
        • Lichtenstein L.
        • Hall J.E.
        Periosteal chondroma; a distinctive benign cartilage tumor.
        J Bone Joint Surg Am. 1952; 24A: 691-697
        • Lewis M.M.
        • Kenan S.
        • Yabut S.M.
        • Norman A.
        • Steiner G.
        Periosteal chondroma.
        Clin Orthop Relat Res. 1990; 256: 185-192
        • Bauer T.W.
        • Dorfman H.D.
        • Latham Jr, J.T.
        Periosteal chondroma.
        Am J Surg Pathol. 1982; 6: 631-637
        • Boriani S.
        • Bacchini P.
        • Bertoni F.
        • Campanacci M.
        Periosteal chondroma.
        J Bone Joint Surg. 1983; 65A: 205-212
        • Karabakhtsian R.
        • Heller D.
        • Hameed M.
        • Bethel C.
        Periosteal chondroma of the rib—report of a case and literature review.
        J Pediatr Surg. 2005; 40: 1505-1507
        • Ly J.Q.
        • Bui-Mansfield L.T.
        • Taylor D.C.
        Radiologic demonstration of temporal development of bizarre parosteal osteochondromatous proliferation.
        Clin Imaging. 2004; 28: 216-218
        • Mora R.
        • Guerreschi F.
        • Fedeli A.
        • Alfarano M.
        • Angi V.
        Two cases of periosteal chondroma.
        Acta Orthop Scand. 1988; 59: 723-727
        • Torreggiani W.C.
        • Munk P.L.
        • Al-Ismail K.
        • O’Connell J.X.
        • Nicolaou S.
        • Lee M.J.
        • et al.
        MR imaging features of bizarre parosteal osteochondromatous proliferation of bone (Nora’s lesion).
        Eur J Radiol. 2001; 40: 224-231
        • Woertler K.
        • Blasius S.
        • Brinkschmidt C.
        • Hillmann A.
        • Link T.M.
        • Heindel W.
        Periosteal chondroma: MR characteristics.
        J Comput Assist Tomogr. 2001; 25: 425-430
        • Ostrowski M.L.
        • Spjut H.J.
        Lesions of the bones of the hands and feet.
        Am J Surg Pathol. 1997; 21: 676-690
        • Twiston Davies C.W.
        Bizarre parosteal osteochondromatous proliferation in the hand.
        J Bone Joint Surg. 1985; 67A: 648-650
        • Horiguchi H.
        • Sakane M.
        • Matsui M.
        • Wadano Y.
        Bizarre parosteal osteochondromatous proliferation (Nora’s lesion) of the foot.
        Pathol Int. 2001; 51: 816-823
        • Lorente Molto F.
        • Bonete Lluch D.J.
        • Marti Perales V.
        Childhood periosteal chondroma.
        Arch Orthop Trauma Surg. 2000; 120: 605-608