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Carpal tunnel syndrome| Volume 32, ISSUE 6, P855-858, July 2007

Muscle Atrophy at Diagnosis of Carpal and Cubital Tunnel Syndrome

  • Paige Mallette
    Affiliations
    Hand and Upper Extremity Service, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA; Orthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Children’s Hospital Boston, Boston, MA.
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  • Meijuan Zhao
    Affiliations
    Hand and Upper Extremity Service, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA; Orthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Children’s Hospital Boston, Boston, MA.
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  • David Zurakowski
    Affiliations
    Hand and Upper Extremity Service, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA; Orthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Children’s Hospital Boston, Boston, MA.
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  • David Ring
    Correspondence
    Corresponding author: David Ring, MD, Orthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Yawkey Center Suite 2100, 55 Fruit Street, Boston, MA 02114
    Affiliations
    Hand and Upper Extremity Service, Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, MA; Orthopaedic Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA; Harvard Medical School, Boston, MA; Children’s Hospital Boston, Boston, MA.
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      Purpose

      This study was designed to test the hypothesis that patients with an initial diagnosis of cubital tunnel syndrome are more likely to present with muscle atrophy than patients with an initial diagnosis of carpal tunnel syndrome.

      Methods

      A list of patients presenting to the office of a single hand surgeon from January 2000 to June 2005 with an initial diagnosis of isolated, idiopathic carpal tunnel syndrome or cubital tunnel syndrome was generated from billing records. The medical records of 58 patients with cubital tunnel syndrome and 370 patients with carpal tunnel syndrome were reviewed for age, gender, diabetes, and presence of atrophy.

      Results

      Twenty-three of 58 patients with an initial diagnosis of cubital tunnel syndrome had atrophy compared with only 62 out 370 patients with an initial diagnosis of carpal tunnel syndrome. Multiple logistic regression revealed that age (odds ratio, 1.06; 95% CI, 1.04–1.08) and diagnosis (cubital tunnel patients were more likely than carpal tunnel patients to present with atrophy; odds ratio, 4.5; 95% CI, 2.7–8.6) were factors significantly associated with atrophy at presentation.

      Conclusions

      Patients with carpal tunnel syndrome present earlier in the course of their disease than patients with cubital tunnel syndrome. Patients with cubital tunnel syndrome are more likely to present with muscle atrophy, reflecting advanced nerve damage that may not respond to surgery.

      Type of study/level of evidence

      Prognostic IV.

      Key words

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