Journal of Hand Surgery
Volume 35, Issue 7 , Pages 1206-1208 , July 2010

Aromatase Inhibitors and Their Side Effects: What Hand Surgeons Should Know

Received 26 November 2009 ,Accepted 7 December 2009.

References 

  1. Dizdar O, Ozcakar L, Malas FU, Harputluoglu H, Bulut N, Aksoy S, et al. Sonographic and electrodiagnostic evaluations in patients with aromatase-inhibitor-related arthralgia. J Clin Oncol. 2009;27:4955–4960
  2. Buzdar A, Howell A, Cuzick J, Wale C, Distler W, Hoctin-Boes G, et al. Arimidex, Tamoxifen, Alone or in Combination Trialists' Group Comprehensive side-effect profile of anastrozole and tamoxifen as adjuvant treatment for early-stage breast cancer: long-term safety analysis of the ATAC trial. Lancet Oncol. 2006;7:633–643
  3. Coleman RE, Bolten WW, Lansdown M, Dale S, Jackisch , Merkel D, et al. Aromatase inhibitor-induced arthralgia: clinical experience and treatment recommendations. Cancer Treat Rev. 2008;34:275–282
  4. Martens HA, Schroder CP, van der Eerden PJM, Willemse PHB, Posthumus MD. Severe disabling tendinopathy caused by anastrozole. Rheumatology. 2007;46:1619–1621
  5. Morales L, Pans S, Paridaens R, Westhovens R, Timmerman D, Verhaeghe J, et al. Debilitating musculoskeletal pain and stiffness with letrozole and exemestane: associated tenosynovial changes on magnetic resonance imaging. Breast Cancer Res Treat. 2007;104:87–91
  6. Morales L, Pans S, Verschueren K, Calster BV, Paridaens R, Westhovens R, et al. Prospective study to assess short-term intraarticular and tenosynovial chances in the aromatase inhibitor-associated arthralgia syndrome. J Clin Oncol. 2008;26:3147–3152
  7. Nishihori T, Choi J, DiGiovanna MP, Thomson JG, Kohler PC, McGurn J, et al. Carpal tunnel syndrome associated with the use of aromatase inhibitors in breast cancer. Clin Breast Cancer. 2008;8:362–365
  8. Sestak I, Sapunar F, Cuzick J. Aromatase inhibitor-induced carpal tunnel syndrome: results from the ATAC trial. J Clin Oncol. 2009;27:4932–4934
  9. Pandya N, Morris GJ. Toxicity of aromatase inhibitors. Semin Oncol. 2006;33:688–695
  10. Conte P, Frassoldati A. Aromatase inhibitors in the adjuvant treatment of postmenopausal women with early breast cancer: putting safety issues into perspective. Breast J. 2007;13:28–35
  11. Brufsky A. Management of cancer-treatment-induced bone loss in postmenopausal women undergoing adjuvant breast cancer therapy: a Z-FAST update. Semin Oncol. 2006;33:S13

 No benefits in any form have been received or will be received related directly or indirectly to the subject of this article.

PII: S0363-5023(09)01111-3

doi: 10.1016/j.jhsa.2009.12.010

Journal of Hand Surgery
Volume 35, Issue 7 , Pages 1206-1208 , July 2010